abstract：PURPOSE:Although gastrointestinal motility disorders are common in critically ill patients, constipation and its implications have received very little attention. We aimed to determine the incidence of constipation to find risk factors and its implications in critically ill patients MATERIALS AND METHODS:During a 6-mo...

journal_title：Journal of critical care

authors： Nassar AP Jr,da Silva FM,de Cleva R

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Data regarding outcome of patients with chronic liver disease with severe hepatic encephalopathy in intensive care unit are currently scarce. METHODS:This study is a retrospective observational case series in a medical intensive care unit (ICU) in a university hospital from 1995 to 2005. Patients with hepatic ...

journal_title：Journal of critical care

authors： Fichet J,Mercier E,Genée O,Garot D,Legras A,Dequin PF,Perrotin D

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:Ventilator-associated pneumonia (VAP) is difficult to diagnose. Recent data suggest quantitative endotracheal aspirate (ETA) may be noninferior diagnostically to quantitative bronchoalveolar lavage (BAL). We hypothesized this would be the case. METHODS:Blind quantitative ETA and BAL were performed on 150 ...

journal_title：Journal of critical care

authors： Medford AR,Husain SA,Turki HM,Millar AB

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess agreement among 4 intensivists in diagnosing myocardial infarction (MI) in critically ill patients based on screening electrocardiograms (ECGs) and cardiac troponin (cTn) levels. METHODS:Consecutive patients admitted to a medical-surgical intensive care unit (ICU) underwent s...

journal_title：Journal of critical care

authors： Lim W,Tkaczyk A,Holinski P,Qushmaq I,Jacka M,Khera V,Devereaux PJ,Terrenato I,Schunemann H,Heels-Ansdell D,Crowther M,Cook D

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:In certain populations, social, legal, and religious factors may influence end-of-life decisions in ventilator-dependent patients. This study aims to evaluate attitudes of first-degree relatives of chronically ventilated patients in Israel, toward end-of-life decisions regarding their loved ones, themselves,...

journal_title：Journal of critical care

authors： Sviri S,Garb Y,Stav I,Rubinow A,Linton DM,Caine YG,Marcus EL

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to analyze the role of tidal volume (Vt) and positive end-expiratory pressure on the oxygenation ratio (OR) (Pao(2)/Fio(2)) during mechanical ventilation (MV) in children with a normal pulmonary gas exchange on admission. METHODS:A retrospective cohort study of children with an...

journal_title：Journal of critical care

authors： Halbertsma FJ,Vaneker M,Pickkers P,Hoeven JG

更新日期：2009-06-01 00:00:00

abstract：:There is a need for neuromuscular relaxant (NMR) agents that are of the "nondepolarizing type" and produce rapidly developing and short-lasting skeletal muscle relaxation in anesthesiology. Many efforts have been directed to produce such agents. Our research focused on the design, synthesis, and evaluation of numerous...

journal_title：Journal of critical care

authors： Gyermek L,Lee C

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Resident physicians' beliefs about cardiopulmonary resuscitation (CPR) may impact their communication with patients about end-of-life care. We sought to understand how these perceptions and experiences have changed in the past decade because both medical education and American society have focused more on th...

journal_title：Journal of critical care

authors： Deep KS,Griffith CH,Wilson JF

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:The aim of the study was to investigate predictors of post-intensive care unit (ICU) in-hospital mortality with special emphasis on the impact of sepsis and organ system failure. METHODS:This study is a subanalysis of the database from the observational Sepsis Occurrence in Acutely Ill Patients study conducted...

journal_title：Journal of critical care

authors： Sakr Y,Vincent JL,Ruokonen E,Pizzamiglio M,Installe E,Reinhart K,Moreno R,Sepsis Occurrence in Acutely Ill Patients Investigators.

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:To study the effects of systemic inflammatory response syndrome (SIRS) on polymorhonuclear neutrophil (PMN) function and phenotype by comparing neutrophils from critically ill patients with SIRS against those from healthy blood donors. MATERIAL AND METHODS:Intensive care unit patients (n = 110) who met at leas...

journal_title：Journal of critical care

authors： Fung YL,Fraser JF,Wood P,Minchinton RM,Silliman CC

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:The objective of this study is to correlate the levels of satisfaction of family members, with their perception of the way information was offered and assistance delivered during the patient's stay in the intensive care unit (ICU). MATERIALS AND METHODS:This is a prospective study conducted in a 13-bed mixed I...

journal_title：Journal of critical care

authors： Fumis RR,Nishimoto IN,Deheinzelin D

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Optimal dosing of antibiotics is important for efficacy and avoidance of resistance. Fluoroquinolones are frequently used to treat severe infections in critically ill patients. We studied ciprofloxacin pharmacokinetics after administration of 400 mg twice a day (bid) intravenously (IV). MATERIAL AND METHODS:Se...

journal_title：Journal of critical care

authors： van Zanten AR,Polderman KH,van Geijlswijk IM,van der Meer GY,Schouten MA,Girbes AR

更新日期：2008-09-01 00:00:00

abstract：:The increasing role of simulation in medical education has paralleled the advancement of this technology. Full environment simulation (FES) can be used to effectively replicate rare medical catastrophes with exacting realism. It has been suggested that emotion can significantly enhance learning by producing memories t...

journal_title：Journal of critical care

authors： Bryson EO,Levine AI

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:In the absence of a reference standard, a probabilistic approach to the diagnosis of ventilator-associated pneumonia (VAP) has been proposed; and clinician judgment augmented by microbiological tests is used to guide therapy for patients having a clinical suspicion of VAP (CSVAP). However, the correlation ...

journal_title：Journal of critical care

authors： Muscedere JG,McColl C,Shorr A,Jiang X,Marshall J,Heyland DK,Canadian Critical Care Trials Group.

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in ventilated critically ill patients. PURPOSE:To develop evidence-based guidelines for the prevention of VAP. DATA SOURCES:MEDLINE, EMBASE, CINAHL, and the Cochrane Database of Systematic Reviews and Register of Control...

journal_title：Journal of critical care

authors： Muscedere J,Dodek P,Keenan S,Fowler R,Cook D,Heyland D,VAP Guidelines Committee and the Canadian Critical Care Trials Group.

更新日期：2008-03-01 00:00:00

abstract：:The aim was to explore how relatives and physicians understood cases where organ donation had been requested and what factors were salient for the decision on donation. Physicians of 25 deceased patients and 20 relatives were interviewed. The material was analyzed using qualitative methods. Eleven patients had declare...

journal_title：Journal of critical care

authors： Sanner MA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Family needs and expectations are often unmet in the intensive care unit (ICU), leading to dissatisfaction. This study assesses cross-cultural adaptability of an instrument evaluating family satisfaction in the ICU. MATERIALS AND METHODS:A Canadian instrument on family satisfaction was adapted for German langu...

journal_title：Journal of critical care

authors： Stricker KH,Niemann S,Bugnon S,Wurz J,Rohrer O,Rothen HU

更新日期：2007-09-01 00:00:00

abstract：:A qualitative research design can provide unique contributions to research in the intensive care unit. Qualitative research includes the entire process of research: the methodology (conceptualization of the research question, choosing the appropriate qualitative strategy, designing the protocol), methods (conducting t...

journal_title：Journal of critical care

authors： Sinuff T,Cook DJ,Giacomini M

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:Given the complexity of biological systems, understanding their dynamic behaviors, such as the Acute Inflammatory Response (AIR), requires a formal synthetic process. Dynamic Mathematical Modeling (DMM) represents a suite of methods intended for inclusion within the required synthetic framework. The DMM, h...

journal_title：Journal of critical care

authors： Vodovotz Y,Clermont G,Hunt CA,Lefering R,Bartels J,Seydel R,Hotchkiss J,Ta'asan S,Neugebauer E,An G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Metabolic acidosis is highly prevalent in critically ill patients with acute renal failure. Little is known about the mechanisms by which renal replacement therapy intervenes in such cases. The objective of this study is to analyze the role of hemodialysis in acidosis correction in intensive care unit patien...

journal_title：Journal of critical care

authors： Libório AB,da Silva Alexandre C,Noritomi DT,Andrade L,Seguro AC

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:The aim of the study is to determine the incidence, demographic risk factors, and outcomes of critical illness among all adult status Aboriginal Canadians (SACs) admitted to intensive care units (ICUs). PATIENTS AND METHODS:A population-based cohort was conducted among adult residents of the Calgary Health Reg...

journal_title：Journal of critical care

authors： Laupland KB,Karmali S,Kirkpatrick AW,Crowshoe L,Hameed SM

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:Pneumothorax is present as a frequent complication in acute respiratory distress syndrome (ARDS). Persistent air leak (PAL) prolongs pneumothorax in 2% of cases of ARDS, increasing the rate of mortality by 26%. Pleurodesis using autologous blood (PAB) is an effective method in cases of oncological pulmonary s...

journal_title：Journal of critical care

authors： Martínez-Escobar S,Ruiz-Bailén M,Lorente-Acosta MJ,Vicente-Rull JR,Martínez-Coronel JF,Rodríguez-Cuartero A

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:This paper describes the methodology of a clinical trial of prone positioning in pediatric patients with acute lung injury (ALI). Nonrandomized studies suggest that prone positioning improves oxygenation in patients with ALI/acute respiratory distress syndrome without the risk of serious iatrogenic injury. It i...

journal_title：Journal of critical care

authors： Curley MA,Arnold JH,Thompson JE,Fackler JC,Grant MJ,Fineman LD,Cvijanovich N,Barr FE,Molitor-Kirsch S,Steinhorn DM,Matthay MA,Hibberd PL,Pediatric Prone Positioning Study Group.

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:Prolonged exposure to normobaric hyperoxia (NH) is associated with blood leukocyte activation and sequestration in the lung. Whether NH-induced leukocyte activation and sequestration can affect extrapulmonary organs or blood cellular profile has not been systematically investigated. We studied simultaneous chan...

journal_title：Journal of critical care

authors： Torbati D,Tan GH,Smith S,Frazier KS,Gelvez J,Fakioglu H,Totapally BR

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:Pediatric venous thromboembolism (VTE) is becoming an increasingly recognized morbidity associated with critical illness. The objective of this survey is to identify the patient factors and radiological features that pediatric intensivists consider more or less likely to make a venous thrombosis (VTE) clinicall...

journal_title：Journal of critical care

authors： Kotsakis A,Cook D,Griffith L,Anton N,Massicotte P,MacFarland K,Farrell R,Hutchison J,Canadian Critical Care Trials Group.

更新日期：2005-12-01 00:00:00

abstract：PURPOSE:The objective of this study is to explore the attitudes, knowledge, and behavior of house staff physicians regarding the use of ultrasound guidance (UG) during central venous catheter placement (CP). MATERIALS AND METHODS:A questionnaire-based study was used to survey house staff in multiple training programs ...

journal_title：Journal of critical care

authors： Girard TD,Schectman JM

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:The criteria for starting extracorporeal membrane oxygenation (ECMO) therapy in term newborn patients with hypoxemic respiratory failure consist of an oxygenation index (OI) of 25 or higher and alveolar-arterial oxygen (Aao(2)) gradient of more than 600 at sea level. In such conditions, inhaled nitric oxide (iN...

journal_title：Journal of critical care

authors： Fakioglu H,Totapally BR,Torbati D,Raszynski A,Sussmane JB,Wolfsdorf J

更新日期：2005-09-01 00:00:00

abstract：:In the past 2 decades, societal spending on health care has become an international concern. The United States currently spends more than 1.6 trillion dollars per year on health care--approximately 15% of the gross domestic product. The provision of care to critically ill patients accounts for a disproportionate share...

journal_title：Journal of critical care

authors： Alsarraf AA,Fowler R

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:Patients with severe penetrating head injury often have a coagulopathy that is difficult to correct. In this report, we describe 3 such patients who were treated with activated factor VII (FVIIa) to stop ongoing hemorrhage that was refractory to conventional treatment. SUBJECTS AND METHODS:We treated 3 patient...

journal_title：Journal of critical care

authors： Aiyagari V,Menendez JA,Diringer MN

更新日期：2005-06-01 00:00:00

abstract：:The science of safety is well established in such disciplines as the automotive and aviation industry. In this brief history of safety science as it pertains to patient care, we review remote and recent publications that have guided the maturation of this field that has particular relevance to the complex structure of...

journal_title：Journal of critical care

authors： Ilan R,Fowler R

更新日期：2005-03-01 00:00:00

abstract：:This paper focuses on the use of data from an electronic medical record (EMR) within a multi-facility health care organization. It describes how health provider workflow is enhanced by extracting data from multiple sources in a near real-time fashion and presenting it to the user in ways that are unavailable in the el...

journal_title：Journal of critical care

authors： Wagner M,Collins B

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the systolic fraction (SF) of the pulmonary venous flow (PVF), measured by transesophageal echocardiography (TEE) could be used to estimate the pulmonary artery occlusion pressure (PAOP). DESIGN:Prospective clinical investigation. PATIENTS:Nineteen intubated patients with ARDS. INTERVE...

journal_title：Journal of critical care

authors： Vargas F,Gruson D,Valentino R,Bui HN,Salmi LR,Gilleron V,Gbikpi-Benissan G,Guenard H,Hilbert G

更新日期：2004-09-01 00:00:00

abstract：:Noninvasive positive pressure ventilation has been demonstrated to be of benefit in preventing endotracheal intubation and reducing mortality in specific patients in the setting of acute exacerbations of chronic obstructive pulmonary disease. The successful application of noninvasive positive pressure ventilation depe...

journal_title：Journal of critical care

authors： Sinuff T,Keenan SP,Department of Medicine, McMaster University.

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To compare the quality of data recorded by a commercially available clinical information system (CIS) to other commonly used methods for obtaining large amounts of patient data. MATERIALS AND METHODS:Five sets of clinical patient data were chosen as a cross-section of all the data collected by a CIS in our int...

journal_title：Journal of critical care

authors： Ward NS,Snyder JE,Ross S,Haze D,Levy MM

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To quantify resource requirements (additional beds and ventilator capacity), for critical care services in the event of pandemic influenza. MATERIALS AND METHODS:Cross-sectional survey about existing and potential critical care resources. Participants comprised 156 of the 176 Australasian (Australia and New...

journal_title：Journal of critical care

authors： Anderson TA,Hart GK,Kainer MA,ANZICS Database Management Committee.

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the pharmacokinetics of individualized amikacin single-dosage regimens targeting low peak serum concentrations in a population of intensive care unit (ICU) patients, and to describe the outcomes associated with this dosing strategy. MATERIALS AND METHODS:In this prospective,...

journal_title：Journal of critical care

authors： Bacopoulou F,Markantonis SL,Pavlou E,Adamidou M

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To describe perceptions of the administrative procedures for seasonal bed closures and their consequences in the intensive care unit (ICU), and to critique this example of health care priority setting for legitimacy and fairness. DESIGN:A qualitative study using case study methods and interviews with key par...

journal_title：Journal of critical care

authors： Rocker GM,Cook DJ,Martin DK,Singer PA

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To identify early mortality-associated clinical risk factors preceding, during, and after cardiac surgery in children. MATERIALS AND METHODS:Of the 722 children admitted to our pediatric intensive care unit (PICU) from January 1992 to January 1997 after repair of congenital heart defects, 70 required 48 hours ...

journal_title：Journal of critical care

authors： Ben-Abraham R,Efrati O,Mishali D,Yulia F,Vardi A,Barzilay Z,Paret G

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:Family-clinician communication in the intensive care unit (ICU) about withholding and withdrawing life support occurs frequently, yet few data exist to guide clinicians in its conduct. The purpose of this study was to develop an understanding of the way this communication is currently conducted. METHODS:We ide...

journal_title：Journal of critical care

authors： Curtis JR,Engelberg RA,Wenrich MD,Nielsen EL,Shannon SE,Treece PD,Tonelli MR,Patrick DL,Robins LS,McGrath BB,Rubenfeld GD

更新日期：2002-09-01 00:00:00

abstract：:The Institute of Medicine's (IOMs) report, "To Err is Human," recently addressed patient safety in the United States, alerting the nation to the need for improved systems of health care. Seven main findings were addressed in this report, we focus on 3: (1) patient safety is a nationwide problem, (2) health care worker...

journal_title：Journal of critical care

authors： Pronovost P,Wu AW,Dorman T,Morlock L

更新日期：2002-06-01 00:00:00